Hepatitis you know what type it is

Hepatitis is accompanied by our life, it is closely related to our lives, it always threatens our physical and mental health. But it's a wide variety of ways to spread, so that we can not be prevented. Its type you know how much? Then I will interpret the type for you. as follows:

Currently recognized at least five kinds of hepatitis virus, namely, hepatitis A virus (HAV), hepatitis B virus (HBV), hepatitis C virus (HCV),

Hepatitis D virus (HDV) and hepatitis E virus (HEV).

Hepatitis A virus (HAV)

Hepatitis A is a type of acute infectious disease caused by hepatitis A virus (HAV). Clinical manifestations of acute onset, chills, fever, loss of appetite, nausea, fatigue, hepatomegaly and abnormal liver function. Some cases of jaundice, asymptomatic cases of infection are more common, generally not to chronic and pathogen carrying state

Hepatitis B virus (HBV)

Hepatitis B virus (HBV) is a genus of liver virus. The complete HBV particles were first found by Dane in the sera of hepatitis B virus infected patients, so called Dane granules. Dane particles are spherical, diameter of 42nm, with double capsid. The outer shell of the virus, the equivalent of the general virus envelope, HBV surface antigen (HBsAg) that is embedded in the coated lipid bilayer, the internal electronic density of a larger core structure, was 20-dimensional stereospecific symmetry, Diameter of about 27nm, the surface of the virus is the underwear shell, underwear shell protein also has antigenicity, as the core antigen of HBV (HbcAg). After exposure to the enzyme or detergent, it exhibits e antigen (HBeAg) with different antigenicity. HbeAg in the body can be secreted and exist in the serum, and HbeAg is only present in the infected liver cell nucleus, generally rarely exist in the serum circulation. HBV core structure of the internal, containing DNA and DNA polymerase. DNA is not completely circular double shares, one of which is a single strand, the length of a single strand in the virus can be different, but not more than half of the full length of the gene. The long strand of viral DNA is negative. While the shorter strand is a positive stock, the virus has a special DNA polymerase, both RNA can be used as a template for transcription of DNA reverse transcriptase function, but also the function of synthetic DNA.

Hepatitis C virus (HCV)

1, acute hepatitis C: adult acute hepatitis C is relatively mild, the majority of acute non-jaundice hepatitis, ALT-based, a small number of acute jaundice hepatitis, jaundice for mild or moderate increase. Can appear nausea, loss of appetite, general weakness, urine yellow eyes and other performance. Hepatitis C virus infection rarely causes liver failure. In the natural state, only 15% of the patients were able to spontaneously clear HCV to heal, and in the absence of antiretroviral intervention, 85% of patients developed chronic hepatitis C; children with acute hepatitis C virus , 50% can spontaneously remove HCV.

2, chronic hepatitis C: mild symptoms, manifested as common symptoms of hepatitis, such as fatigue, poor appetite, abdominal distension and so on. Can also be without any symptoms. ALT repeated test, HCV RNA continued positive. 1/3 of chronic HCV infection has been normal liver function, anti-HCV and HCV RNA continued positive, liver biopsy showed chronic hepatitis, and even found cirrhosis.

3, hepatitis C cirrhosis: infection HCV 20 - 30 years 10% to 20% of patients can develop cirrhosis, 1% to 5% of patients with hepatocellular carcinoma can lead to death. Cirrhosis once the decompensation situation, such as jaundice, ascites, variceal bleeding, hepatic encephalopathy, etc., the survival rate is sharply reduced.

Hepatitis D virus (HDV)

Hepatitis D virus is a defective virus, the completion of its biological cycle depends on the help of hepatitis B virus, so hepatitis D can not exist alone, must be in the presence of HBV to infection and cause disease, thus , Hepatitis D and hepatitis B to overlap infection or infection in the form of the existence of its transmission and hepatitis B similar to the prevalence of infection in southwestern China, HBsAg positive in the population of Dinggan infection rate of more than 3% Humans are generally susceptible to HDV.

Hepatitis E virus (HEV)

HEV is a single stranded positive strand RNA virus, spherical, diameter 27 ~ 34nm without capsule, nucleocapsid was icosahedral three-dimensional symmetry. At present, it is not possible to organize tissue culture in vitro, but chimpanzees, cynomolgus monkeys, rhesus monkeys, African green monkeys, marmosets are sensitive to HEV and can be used to isolate viruses. HEV in the alkaline environment is stable, magnesium, manganese ions exist in the case of maintaining its integrity, sensitive to high heat, boiling can be inactivated. (ORF1) at the 5 'end (about 2kb) is a non-structural protein gene, RNA-dependent RNA polymerase sequence, ORF2 is located in the 3' (About 2kb) is a major part of the structural protein, which can encode the nucleocapsid protein. ORF3 is overlapped with ORF1 and ORF2 (369bp in length) and is a viral structural protein gene that encodes a virus-specific immune response antigen.